December 21, 2009

New Findings May Help Ensure The Safe And Effective Use Of Opioid Medications

At a time when prescription opioid abuse and misuse has become a major public health concern, new research may help clinicians and health care organizations determine the best approach for assessing the risk of abuse prior to initiating opioid therapy.

In a study to assess the sensitivity of common screening tools for predicting aberrant drug-related behavior, researchers found that the Screener and Opioid Assessment for Patients with Pain (SOAPP), a brief, pen-and-paper self-report tool, is a highly sensitive instrument.

The study, conducted by researchers including leading pain specialist Steven D. Passik, Ph.D., compared the sensitivity of a semi-structured clinical interview and three screening tools: the SOAPP, the Diagnosis, Intractability, Risk, and Efficacy inventory (DIRE), and the Opioid Risk Tool (ORT). Results showed the highest sensitivity for the clinical interview (0.77) and the SOAPP (0.72), followed by the ORT (0.45). and the DIRE (0.17). In addition, the researchers found that combining the clinical interview with the SOAPP increased sensitivity to 0.90.

The findings appear in the current issue of Pain Medicine (Volume 10, Issue 8, pages 1426-1433).

“This study is important because it provides new evidence that opioid risk assessment screening tools such as the SOAPP can increase the predictive power of the clinical interview, which is the foundation of the process,” says Kevin Zacharoff, M.D., Director of Medical Affairs at Inflexxion. “As we look ahead to the increased awareness of assessing opioid risk, and likely implementation of federally required Risk Evaluation and Mitigation Strategies (REMS) for opioid medications, we may begin to see more health care organizations and clinicians evaluating and incorporating these tools into the clinical workflow, so they can take an evidence-based approach to ensuring that opioid medications are used safely and effectively.”

Developed by researchers at Inflexxion, the SOAPP is formally licensed for use at more than 50 health care organizations across the nation, including Kaiser Permanente. It is also available directly for individual clinical use at no cost to clinicians who register at PainEDU.org, Inflexxion’s award-winning educational website for health care professionals who prescribe pain medications.

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